Unless they have changed things for the hybrid (not like Honda to do that sort of change) normal behavior is that grabbing the door handle unlocks the door. If the vehicle is unlocked and you grab the door handle it should do nothing.
Are you sure you are not touching the button spot when you open the door with the handle?
If you are certain you are not touching the little button, then maybe have it evaluated by your dealer. Pushing the little button spot on the top of the handle locks the door.
Door handle was not wet was it? I ask because both the unlock and lock features are touch sensitive triggers, and a wet handle can confuse the lock and unlock sometimes (found that out washing my vehicle with my FOB in my pocket).