The Rav4 and even the hybrid has a full sized spare. Only the next years plug in has a run flat.Run flat tires are extremely expensive, and they only last about 50 miles or so with zero air. They are a solution of choice by some premium car brands, but when the tires cost 2-4x what a regular tire costs.. and are still ending up destroyed by something more severe then a simple puncture... owners are generally angry about it.
A friend of ours owns an Audi A4. Came with run-flats, and she lost one to a road hazard. Dealer price= $600 (though you can get them online for about half that of course).... but it gets worse... dealer advised here that she had to replace all four.. not just the failed one... so she was very upset about the outcome, after initially loving the idea of run-flats instead of a spare. She did end up buying a full set for $1200 off of Amazon and then paid a local tire shop to install them. Audi dealer wanted almost $2700 for the same result.
If my next vehicle (which will be a compact SUV, and probably a CRV) has no spare.. I will be buying and placing a spare in my cargo hold... which further argues in favor of a CRV.. since it generally has best in class cargo space. For an SUV.. a covered spare tire enclosure in the cargo rack above would work too.. and that may in fact become an after market thing for the SUV/CUV market in coming years... as this is ripe for enterprising entreprenurs to go after.
The reason you have to replace all on an axle or all four on a 4WD is an imbalance in the tread depth and thus a confused traction control system. And that is with or without run flats. Had a delamination years ago on a rental car in Germany and was fun getting the rental company to buy two tires. Germany has strict rules and the shop wouldn't sell only one. This even with no traction control.